What is the main source of the protein called mitochondrial coxiella effector F?
Bacteria
2024 January
|
|
5/5 |
An antioxidant protein called mitochondrial coxiella effector F (MceF), which is generated by the intracellular Gram-negative bacterium Coxiella burnetii, has been discovered by researchers. Despite a high bacterial load, MceF promotes the health of human cells. When Coxiella burnetii invades its host cells, it releases MceF and interacts with the mitochondrial glutathione peroxidase 4 (GPX4). By improving mitochondrial function, this interaction shields mammalian cells from the harm and death caused by pathogen replication. The recently discovered protein exhibits possible medicinal uses.